Alcohol And the Gastrointestinal Tract: Special Issue: by M. V. Singer, D. Brenner PDF

By M. V. Singer, D. Brenner

ISBN-10: 3805580304

ISBN-13: 9783805580304

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Extra info for Alcohol And the Gastrointestinal Tract: Special Issue: Digestive Diseases 2005

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Alcohol Effect on Saliva and Salivary Glands Clinical enlargement of the parotid gland is often present in chronic alcoholics [79, 80]. Investigating the effect of chronic ethanol consumption on salivary gland morphology and function in a rat animal model, Maier et al. [81] found fat accumulation in acinar cells along with a reduction in weight and protein content of the parotid gland. Maier et al. [81] also demonstrated a re- Alcohol-Related Diseases of the Mouth and Throat duction in salivary flow rates based on experiments in their animal model.

51 Simanowski UA, Seitz HK, Baier B, Kommerell B, Schmidt-Gayk H, Wright NA: Chronic ethanol consumption selectively stimulates rectal cell proliferation in the rat. Gut 1986;27: 278–282. 52 McGarrity TJ, Peiffer LP, Colony PC, Pegg AE: The effects of chronic ethanol administration on polyamine content during dimethylhydrazine-induced colorectal carcinogenesis in the rat. Carcinogenesis 1988;9:2093–2098. 53 Seitz HK, Czygan P, Simanowski U, Waldherr R, Veith S, Raedsch R, Kommerell B: Stimulation of chemically induced rectal carcinogenesis by chronic ethanol ingestion.

Further prolonged alcohol administration with an intragastric cannulae inhibited the recovery, and resulted frequently in parenchymal calcifications. Pancreatic regeneration was less pronounced in ethanol-fed animals, and calcifications remained in some animals [81]. Hyperstimulation of the pancreas with supramaximal doses of CCK increases exocrine pancreatic secretion and induces acute edematous pancreatitis. Rats received an ethanol diet for 2 or 6 weeks according to the TsukamotoFrench model [82].

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Alcohol And the Gastrointestinal Tract: Special Issue: Digestive Diseases 2005 by M. V. Singer, D. Brenner


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